This open-label, randomized, controlled, crossover trial assessed the effect of daily virgin oil oil VCO consumption on plasma lipoproteins levels and adverse events. The study population was 35 healthy Thai volunteers, aged 18— After 8 weeks, participants had an 8-week washout period and then crossed over to take the alternative regimen for 8 weeks.
Plasma lipoproteins levels were measured in participants at baseline, week-8, week, and week follow-up visits. Of 32 volunteers with complete follow-up 16 males and 16 femalesdaily VCO intake virgin increased high-density lipoprotein cholesterol by 5.
However, there was no difference in cholesterol change in total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels between the two regimens.
Mild diarrhea was reported by some volunteers when taking VCO, but no serious adverse events were reported.
No major safety issues of taking VCO daily for 8 weeks were reported. Consumption of saturated fatty acids SFAs in coconut diets has been attributed to increased risk of cardiovascular disease CVD [ 1 ]. Indeed, several guidelines for the prevention of reduce disease recommend decreasing the intake of SFAs to reduce the risk of developing CVD [ 1 can, 3 — fifty plus milfs ].